Thats interesting. Maybe we're just not searching in overlapping sectors and having different experiences? I was curious by your account so I asked it who Aviv Regev is, who is certainly a famous figure in my line of work but not a household name by any stretch. It provided a quick and accurate summary of who she is.

>Aviv Regev is a computational biologist and systems biologist who is currently the Executive Vice President and Head of Genentech Research and Early Development in Genentech/Roche¹. She is also a core member (on leave) at the Broad Institute of MIT and Harvard and a professor (on leave) at the Department of Biology of the Massachusetts Institute of Technology¹. She is a pioneer of single cell genomics and of computational and systems biology of gene regulatory circuits¹. She founded and leads the Human Cell Atlas project, a global initiative to map all the cell types in the human body¹ .

>Source: Conversation with Bing, 4/20/2023 (1) Aviv Regev - Wikipedia. https://en.wikipedia.org/wiki/Aviv_Regev. (2) Aviv Regev | Biomathematics @Harvard. https://biomath.fas.harvard.edu/people/aviv-regev. (3) Aviv Regev: H-index & Awards - Academic Profile | Research.com. https://research.com/u/aviv-regev.

I then asked it to provide some of her recent pubs and it also performed well.

>Sure, here are some of her recent publications from various sources:

>- SlideCNA: Spatial copy number alteration detection from Slide-seq-like spatial transcriptomics data¹

• Single-cell multi-omics reveals dynamics of purifying selection of pathogenic mitochondrial DNA across human immune cells¹
• Emergence of division of labor in tissues through cell interactions and spatial cues¹
• Cell-subtype specific effects of genetic variation in the aging and Alzheimer cortex¹
• Learning Causal Representations of Single Cells via Sparse Mechanism Shift Modeling¹
• Systematically characterizing the roles of E3-ligase family members in inflammatory responses with massively parallel Perturb-seq¹
• Compressed Perturb-seq: highly efficient screens for regulatory circuits using random composite perturbations¹
• Cellular dynamics across aged human brains uncover a multicellular cascade leading to Alzheimer's disease¹
• Pancreatic cancer risk predicted from disease trajectories using deep learning²
• Cell-type specific developmental defects in PTEN-mutant cortical organoids converge on abnormal circuit activity³

>Source: Conversation with Bing, 4/20/2023 (1) Aviv Regev's research works | Broad Institute of MIT and Harvard, MA .... https://www.researchgate.net/scientific-contributions/Aviv-Regev-38194627. (2) Genentech: Aviv Regev | Head, Executive Vice President, Genentech .... https://www.gene.com/scientists/our-scientists/aviv-regev. (3) Aviv Regev - Publications. https://academictree.org/cellbio/publications.php?pid=874364. (4) Regev Lab | Broad Institute. https://www.broadinstitute.org/regev-lab. (5) Webinar: Expert Talk with FNIH Lurie Prize Winner Dr. Aviv Regev ... - nyas. https://www.nyas.org/events/2021/webinar-expert-talk-with-fnih-lurie-prize-winner-dr-aviv-regev-phd/.

It was very obvious. The way the stock price moved so quickly after CVNA announced their partnership with PTEN was a clear signal that something fishy was going on.

XOM, OXY, CVX, MRO, or DVN are all good oil stocks. Or you could by an oil service company like HAL, SLB, NOV, or PTEN.

Puts on pten

I think the play is HP, PTEN, HAL, or NOV. Already loaded up on oil stocks, but the services are still cheap. Only a matter of time before they make a run.

Exxon releases earnings pre-market on Friday. I’m very curious how that one turns out. PTEN does seem to have some cheap options.

Pten

Pls fly

AMD 6/17 120C

AB 4/14 50C

COST 3/4 525C

DE 2/18 400C

ETSY 2/25 143C

OPEN 3/4 10.5C

PTEN 1/20/23 10C

RDFN 2/18 32C

SENS 3/18 3C

SENS 1/19/24 3.5C

DIS 3/18 155C

Oil drillers stand a lot to gain from this Ukraine situation.

Keep an eye PTEN

There is a lot missing from your post regarding these investments. For example, are they in a retirement fund such as an IRA? Or in a market investment account on which you have to pay taxes? If it is a taxable account, at least part of your investments could be sold so you can claim the tax loss. Invest the proceeds in a straight market fund instead of a focused fund such as these.

Just general perspective, these funds were hot a year ago. For the most part, they won't move up because the fundamentals (the underlying stocks) are not moving. So what is moving? Some technology stocks are moving. Some fintech stocks are moving. Some health care stocks are moving. Do a focused deep dive to find companies that are benefiting from current events and invest accordingly.

What is not moving? Most genomics stocks are flat at best or overvalued at worst. Most heavy industry stocks are in the doldrums. Energy stocks have done very well over the last 2 years, but currently appear flat to slightly downward trending.

https://finance.yahoo.com/quotes/PXD,EOG,PSX,XOM,VLO,HP,HES,COP,APC,NOV,BP,DVN,SU,CLR,PTEN,PHX,GPOR,LPI,OAS,NBR,WLL,CHK,GTE/view/v1

You CAN go out then come back in. PTEN, a contract oil driller who rents out and operates oil rigs. Been doing that for 16 years now with PTEN and made several small fortunes going in and out several times. Building right now. Someday PTEN will stop producing--but all oil wells eventually do that anyways!

Not much. Wished had shorted at a higher price but 234 was what was available nine days ago. Go to cool off at the Senior Center then work tonight because Don't Quit Your Day Job! Oh, PTEN has crossed 10usd; when it gets to 30usd I'm out making almost 90000usd. PTEN has been an interesting adventure in oil-drilling: buy at the valleys and sell at the peaks. That's all.

Same here. I’ve made a good amount so far with GME and a bit of AMC. Also made good money off SNDL, NOK, and BB calls during the first run up.

Other good plays I’ve enjoyed: riding the JETS ETF with calls when it’s low and selling when it rises, then repeat once it drops again. VEEV has been consistently growing over the past couple years for me. DVN and OXY in energy.

DFV’s late 2020-early 2021 portfolio, which you can find in his old YouTube videos (Roaring Kitty) have all done incredibly well (year gains below):

• PTEN (energy): +130% for the year
• SD (energy): +276%
• PUMP (energy): +127%
• NGD (gold): +80%
• RRC (energy): +129%
• PRTY (retail): +675% (!!!)
• CVGI: 362%
• CNR: 190%
• OLM: 255%
• AR: 300%
• RFP: 620%
• GME: 6226% (🤯)

Dude put the work into his value plays that’s for sure.

Bezos is Getting Out While The Gettin's Good, looks like. Reminds me of when the '87 market crash happened some reporters went to Sam Walton down in Arkansas to ask for a story--they found him just coming in in his old beat-up pickup. When told he had lost one billion that day, Sam replied, "Good! I have six more left!". Makes me wonder if I should sell some of my GLW and a few other things. What GME is to most Redditors PTEN is to me--and I'm stayin' in! Been makin' Serious Money in PTEN for 16 years..

Anybody else making money on $ pten, up twenty two percent this week, my $9 calls bought on 4/19 are on fire, that and my calls for $ cg are on fire this will be a great return all year

Fuck yeah, PTEN

PTEN upgraded on short squeeze

Bought PTEN not realizing DFV last “Cheers” video was from months ago (where he highlight PTEN in his spreadsheet). True ape.

Is this a subtle way to say pten is the next play?

Anyone wondering if this is a subtle nod to PTEN?

Well turns out I have to wait for my deposit to approve, didn’t realize I can’t trade options on margin. So I actually put 1 call in on pten for $10. Considering oil has been going up. I’m new to options so I’m prob not the best one to ask haha

What about pten, nov, chkaq? Does anyone have opinions on these stocks?

PTEN

https://finviz.com/quote.ashx?t=PTEN

I bought this morning.

Patterson-UTI Energy (PTEN) is at $4.52 (+3.43%) on investing.com

http://www.investing.com/equities/patterson-uti-energy-inc?utm_source=investing_app&utm_medium=share_link&utm_campaign=share_instrument

Which PTEN are you looking at?

Did you buy PTEN?

PTEN sell at 5.50ish

Opened up my next positions today; KO 7/2 - 50.5c avg .85 (7) Everi 7/17 - 12.5c avg .70 (15) DFEN 7/17 - 25c avg 1.1 (9) MRO 7/17 - 9c avg .60 (10) RDSA 7/17 - 45c avg .34 (58) PTEN 7/17 - 8c avg .25 (5) HAL 10/16 -23c .23 (1) 28c .19 (1) 29c .17 (1) 30c .09 (3)

$CPE $WPX $SLB $DVN $ESTE $PTEN $REI $TS $NE

I literally just threw all my money at spy, tsla, dal, and pten puts yesterday, hopefully it pays off

PTEN

Momentum on PTEN? Multi-day breakout

Predicted 30 percent breakout on PTEN at market open

Potential breakout on PTEN ? See it could possibly rip through resistance.. been seeing a lot of panic activity recently.. lmk

This is the bear porno I subbed for

Oil drill companies $BKR, $HAL, $PTEN, $HP

Short that shit gays

blindly sets up puts for $BKR, $HAL, $PTEN, $HP in the morning

Nabors has a bunch of international shit. HP has a couple of rigs outside the US. PTEN is all in the US and mostly WTX (DJ/Perm) or Marcellus. Don't know much about the drilling side as I was on the completions side.

Drilling and service companies will get hammered first.

Operators will be hit or miss, it depends on current financials as well as how well they are hedged on production. Some are already fucked like Chesapeake $CHK, others like $EOG might just weather the storm. They will all see dips with the news, but some will be harder hit than others and might not recover.

Drilling and service will likely take the hardest hits, $BKR, $HAL, $PTEN, $HP since their businesses are so dependent upon drilling and completions activities.

Oil has been down so long that a lot of these companies don’t have a lot of blood left to lose. Buyouts and bankruptcies are on the horizon.

Trade riggers, they are way undervalued right now. I think they have much more to go. KEG, RIG, VAL, PTEN, SDRL, HP

I'm not familiar with oil but i googled analyst predictions for the OPEC meeting and first result was Goldman Sachs they're super bullish and predicting it'll reach $80/barrel for 2H.

I also sorted Independent Oil & Gas and Oil & Gas Drilling & Exploration industries in Finviz, the most doable stock that has good option liquid are:

$WLL, $CXO, $COP, $CPE, $PTEN, $RIG, $NBR

All of these stocks has 2b+ market cap, above 1m volume and 1k++ Open Interest w/ massive calls, how about you? are you just getting the ETF? or you're eyeing on a stock? :)

Several hundred thousand shares? Yeesh. I was pissed with several thousand shares.

The whole bankruptcy thing always seemed fishy for current employees, and the fact that we emerged so fast out of it just raised some red flags, I guess for some good (they got to keep their job, which according to management was never at risk because of the the bk), and for some, like me that actually had money invested on my 401k and was taking advantage of the company match, was pissed and could do absolutely nothing about it, all while top brass came out like bandits.

I consider myself a former employee of said company, because I want to be as detached from that shitshow that SSE was as much as possible. I'm currently with PTEN and honestly everything is looking much better. At least they don't make us wait 5 years till we get fully vested on our 401k. PTEN is 100% vested on payday.

I am typically a distressed debt investor but I bought SSE betting that CHK would have to bail them out or face fraudulent transfer lawsuits. I bet wrong but owned several hundred thousand shares. I am extremely familiar with the entire situation.

Essentially CHK loaded up the company with debt to avoid tripping their own covenants and then cut SSE's dayrates in order to preserve CHK liquidity. I believe that PTEN approached SSE before SSE filed for chapter 11 and said something to the effect of, we want to buy you out but you need to get rid of the debt. SSE set up literally the fastest chapter 11 I have ever seen (I think it was like 20 days) tossed the keys to the creditors so they would go along and then began negotiating with PTEN upon emergence knowing full well that the previous shareholders warrants wouldn't vest.

Glad to hear they are doing better but they still put their own employees on the chopping block which is a cold move. Is that why you are a former employee?

PTEN in late 2014

PTEN is obviously not an oil giant, but their history has proven that they can weather a storm. They have excellent debt management and I have no doubt that they will come back as the price of oil increases once again. I bought half of my intended position and my next move will depend on their earnings report in three weeks.

Thanks, JaqueHoff.

What are your thoughts on $PTEN? You ready to jump in?

It's all driven by oil prices, and right now it's not looking good. I sold my oil & gas holdings a couple of months ago for a loss, but in hindsight I'm glad I did because they are more than 20% lower than when I got out.

Keep an eye on oil prices, and follow OPEC news.

PTEN looks like a decent company and their dividend has been increasing. But again, their business model may not be profitable with oil < $70 a barrel.

This is not really a fair response to the article. The article explicitly addresses the different treatments for different cancers, it advocates the principle of vaccines as a treatment for a class of disease, one they have not really been adapted to previously.

In fact, many cancers do have a lot in common, though they use different pathways to achieve immortality, many have disruptions to common apoptopic mechanisms with key genes/proteins like KRAS and PTEN being common problems. The idea of stimulating immune responses as a course of treament to cancer in general is a perfectly valid classification of these approaches, though not the only one.