Crinetics Pharmaceuticals, Inc.

Crinetics Pharmaceuticals, Inc.

CRNX
Crinetics Pharmaceuticals, Inc.US flagNASDAQ Global Select
34.47
USD
+0.94
- -
3.63BMarket Cap
2016 Y
2017 Y
2018 Y
2019 Y
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
- -
- -
- -
- -
- -
0.03
0.09
0.07
0.01
0.08
0.19
Basic EPS, GAAP
-0.43
-0.66
-2.23
-2.09
-2.42
-2.8
-3.15
-3.69
-3.69
-4.95
-5.13
Free Cash Flow per Basic Share
-0.41
-0.7
-1.69
-1.94
-2.04
-2.32
-2.25
-2.98
-2.9
-4.08
-4.33
Dividend per Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Book Value per Share
-0.51
-1.17
13.19
4.84
5.55
8.65
6.16
9.27
16.39
10.53
13.25
Tangible Book Value per Share
-0.45
-1.08
13.2
4.85
5.55
8.64
6.09
9.28
16.4
10.55
13.23
Basic Weighted Avg Shares
14
14
12
24
30
38
52
58
81
94
97
Sales/Revenue/Turnover
- -
- -
- -
- -
- -
1
5
4
1
8
18
Operating Margin (%)
- -
- -
- -
- -
- -
-9,990.91
-3,544.06
-5,547.17
-32,613.47
-6,714.77
-3,020.32
Depreciation Expense
- -
- -
- -
1
1
1
1
1
3
4
4
Net Income, GAAP
-6
-9
-27
-50
-74
-108
-164
-215
-298
-465
-496
Effective Tax Rate (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Profit Margin (%)
- -
- -
- -
- -
- -
-9,985.25
-3,460.38
-5,345.85
-28,720.69
-6,046.22
-2,747.18
Working Capital
11
14
159
115
167
329
317
530
1,316
963
1,251
LT Debt
- -
- -
- -
5
4
3
2
48
45
42
41
Total Equity
-6
-15
160
117
169
332
316
539
1,325
992
1,281
Return on Invested Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Common Equity (%)
- -
- -
- -
-36.39
-51.64
-42.95
-50.24
-49.98
-32.05
-40.21
-39.16

Capital Structure

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
ST Debt
6
6
7
LT Borrowings
- -
- -
- -
LT Finance Leases
43
42
41
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
95
96
105
Market Capitalization
3,880
4,378
3,516

Working Capital

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
Total Current Assets
1,121
1,048
1,322
Cash, Cash Equivalents & STI
1,092
1,028
1,291
Accounts Receivable, Net
- -
1
6
Inventories
- -
2
3
Total Current Liabilities
74
85
71
Payables & Accruals
34
42
37
ST Debt
6
6
7
Deferred Revenue
2
1
1

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
- -
56.57%
-25.11%
Free Cash Flow
- -
44.33%
63.94%
Net Income, GAAP
- -
44.8%
55.93%
Sales/Revenue/Turnover
- -
- -
640.71%
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
1
- -
- -
- -
1
2025
- -
1
- -
6
8
2026
11
- -
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
-0.93
-0.94
-0.96
-0.88
-3.69
2025
-1.04
-1.23
-1.38
-1.29
-4.95
2026
-1.23
- -
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Company Description

MCPAPIChat
CEO
R. Scott Struthers
Full Time Employees
437
Sector
Healthcare
Industry
Biotechnology
Address
Building No. 2 San Diego CA United States of America 92121
IPO Date
Jul 18, 2018
Business
Crinetics Pharmaceuticals, Inc. (Nasdaq: CRNX) develops novel oral small-molecule therapeutics for rare endocrine diseases and endocrine-related tumors; its approved lead product PALSONIFY (paltusotine), a once-daily selective somatostatin receptor type 2 (SST2) nonpeptide agonist, treats adults with acromegaly who had an inadequate response to surgery or for whom surgery is not an option, while also advancing in Phase 3 for carcinoid syndrome associated with neuroendocrine tumors (NETs); late-stage pipeline includes atumelnant (CRN04894), an oral melanocortin type 2 receptor (MC2R) antagonist in Phase 2/3 for classic congenital adrenal hyperplasia (CAH) and ACTH-dependent Cushing’s syndrome; CRN09682, a first-in-class nonpeptide drug conjugate (NDC) delivering monomethyl auristatin E (MMAE) to SST2-expressing tumors including NETs and other solid tumors, with Phase 1/2 dosing initiated in December 2025; early-stage candidates in IND-enabling studies comprise a TSH antagonist for Graves’ hyperthyroidism and orbitopathy (thyroid eye disease), SST3 agonist for autosomal dominant polycystic kidney disease (ADPKD), and PTH antagonist for hyperparathyroidism. Founded in 2008 by Scott Struthers and colleagues with endocrinology expertise from Neurocrine Biosciences, the company is headquartered in San Diego, California, with an additional office in Zug, Switzerland, and operates globally with a focus on GPCR-targeted therapies discovered in-house. Recent developments include FDA approval of paltusotine in 2025 with commercialization underway, first patient dosing in the CRN09682 Phase 1/2 trial in December 2025 marking a milestone for its NDC platform, first patient randomization in the pivotal Phase 3 CAREFNDR trial for paltusotine in carcinoid syndrome, a $350 million oversubscribed private placement in early 2024 to fund R&D and operations, and a partnership with Sanwa Kagaku Kenkyusho for paltusotine commercialization in Japan.

Company News

MCPAPIChat
  • Crinetics Presents Long Term Data at ENDO 2026 Confirming PALSONIFY™ (paltusotine) Provides Durable, Consistent Acromegaly Control

  • Crinetics Presents Long Term Data at ENDO 2026 Confirming PALSONIFY™ (paltusotine) Provides Durable, Consistent Acromegaly Control

  • Crinetics and Leading Patient Groups Launch ‘Everyday Advocacy' Initiative to Empower People Across Endocrine Disease Communities

  • Crinetics’ Paradigm-Shifting Portfolio and Pipeline on Display at ENDO 2026 with Six Presentations

  • Crinetics' Paradigm-Shifting Portfolio and Pipeline on Display at ENDO 2026 with Six Presentations

  • Crinetics Pharmaceuticals to Participate in Jefferies Global Healthcare Conference 2026

  • Hedge Fund Drops $37 Million on Rare Disease Biotech Crinetics. Is It a Buy?

  • Crinetics Pharmaceuticals, Inc. (CRNX) Q1 2026 Earnings Call Transcript

  • Crinetics Pharmaceuticals, Inc. (CRNX) Reports Q1 Loss, Beats Revenue Estimates

  • Crinetics Pharmaceuticals Reports First Quarter 2026 Financial Results and Provides Business Update

  • Analysts Estimate Crinetics Pharmaceuticals, Inc. (CRNX) to Report a Decline in Earnings: What to Look Out for

  • Crinetics Pharmaceuticals Announces the European Commission Approval of PALSONIFY® (Paltusotine) for the Treatment of Acromegaly in Adults

  • Jeff Knight Sells 85,163 Shares of Crinetics Pharmaceuticals (NASDAQ:CRNX) Stock

  • Crinetics Pharmaceuticals to Report First Quarter 2026 Financial Results on May 7, 2026

  • Crinetics Pharmaceuticals, Inc. (NASDAQ:CRNX) Receives Average Recommendation of “Moderate Buy” from Analysts

  • Crinetics Director Sells 5,000 Shares With Stock Down 4%, but Here's What Matters More

  • Crinetics Pharmaceuticals Announces Submission of Marketing Authorization Application in Brazil for Palsonify™ (Paltusotine) in Acromegaly

  • Crinetics Pharmaceuticals Highlights Early PALSONIFY Sales, EU Milestone, and GPCR Pipeline at TD Cowen Conf.

  • Intech Investment Management LLC Has $926,000 Stock Position in Crinetics Pharmaceuticals, Inc. $CRNX

  • Crinetics Pharmaceuticals, Inc. (CRNX) Q4 2025 Earnings Call Transcript