CRISPR Therapeutics AG

CRISPR Therapeutics AG

CRSP
CRISPR Therapeutics AGUS flagNASDAQ Global Market
51.52
USD
+1.30
- -
4.98BMarket Cap
2014 Y
2015 Y
2016 Y
2017 Y
2018 Y
2019 Y
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
- -
0.01
0.42
1.02
0.07
5.32
0.01
12.02
0.01
4.67
0.41
- -
0.12
Basic EPS, GAAP
-0.23
-0.88
-1.89
-1.71
-3.44
1.23
-5.29
4.97
-8.36
-1.94
-4.34
-6.47
-4.76
Free Cash Flow per Basic Share
-0.16
1.99
-4.56
-1.94
-2.06
0.92
-3.89
6.02
-6.85
-3.44
-1.71
-4.12
-3.92
Dividend per Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Book Value per Share
-0.18
-0.73
5.86
4.63
7.56
15.46
22.52
31.17
23.89
23.52
22.53
20.04
18.07
Tangible Book Value per Share
-0.19
-0.74
5.85
4.62
7.56
15.45
22.51
31.16
23.89
23.52
22.53
20.04
18.07
Basic Weighted Avg Shares
29
29
12
40
48
54
66
76
78
79
84
90
95
Sales/Revenue/Turnover
- -
- -
5
41
3
290
1
913
- -
370
35
- -
11
Operating Margin (%)
- -
-10,416.6
-1,319.33
-157.69
-5,087.8
16.14
-65,273.48
40.91
-154,394.72
-60.15
-1,333.05
- -
-4,857.64
Depreciation Expense
- -
- -
1
3
4
5
9
18
24
20
19
19
19
Net Income, GAAP
-7
-26
-23
-68
-165
67
-349
378
-650
-154
-366
-582
-451
Effective Tax Rate (%)
- -
- -
- -
- -
- -
0.67
- -
0.49
- -
- -
- -
- -
- -
Profit Margin (%)
- -
-10,456.68
-449.3
-166.74
-5,281.08
23.09
-64,247.7
41.36
-149,122.71
-41.52
-1,046.43
- -
-4,101.26
Working Capital
-1
147
298
234
439
930
1,622
2,298
1,732
1,799
1,849
1,837
2,239
LT Debt
- -
38
- -
- -
- -
44
50
213
228
223
206
188
765
Total Equity
-7
-29
233
188
392
939
1,664
2,399
1,875
1,883
1,932
1,922
1,747
Return on Invested Capital (%)
- -
- -
- -
- -
- -
6.7
- -
17.04
- -
- -
- -
- -
- -
Return on Capital (%)
- -
- -
- -
- -
- -
9.66
- -
17.36
- -
- -
- -
- -
- -
Return on Common Equity (%)
- -
- -
- -
-32.5
-56.89
10.04
-26.8
18.59
-30.42
-8.17
-19.2
-30.18
-26.09

Capital Structure

FRC

•

in mil. unless spec.
Dec'25
Mar'26
Jun'26
ST Debt
19
19
19
LT Borrowings
- -
585
586
LT Finance Leases
188
184
179
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
96
96
97
Market Capitalization
5,029
4,585
5,272

Working Capital

FRC

•

in mil. unless spec.
Dec'25
Mar'26
Jun'26
Total Current Assets
1,986
2,448
2,372
Cash, Cash Equivalents & STI
1,976
2,442
2,364
Accounts Receivable, Net
- -
- -
- -
Inventories
- -
- -
- -
Total Current Liabilities
149
136
133
Payables & Accruals
102
89
82
ST Debt
19
19
19
Deferred Revenue
16
15
15

Growth Rates

FRC

•

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
-56.85%
4.96%
-0.53%
Free Cash Flow
-132.74%
-86.81%
156.39%
Net Income, GAAP
-79.61%
-71.91%
58.8%
Sales/Revenue/Turnover
- -
- -
- -
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

•

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
35
35
2025
- -
- -
- -
- -
- -
2026
1
10
- -
- -
- -

Quarterly Earnings Per Share

FRC

•

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
-1.43
-1.49
-1.01
-0.44
-4.34
2025
-1.58
-2.4
-1.17
-1.37
-6.47
2026
-1.28
-0.94
- -
- -
- -

Quarterly Dividends Per Share

FRC

•

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Company Description

CEO
Samarth Kulkarni
Full Time Employees
393
Sector
Healthcare
Industry
Biotechnology
Address
Baarerstrasse 14 Zug ZG Switzerland 6300
IPO Date
Oct 19, 2016
Business
CRISPR Therapeutics AG (Nasdaq: CRSP) is a biotechnology company focused on developing transformative gene-based medicines for serious diseases using its proprietary CRISPR/Cas9 gene-editing platform. Founded in 2013 and headquartered in Zug, Switzerland, the company operates globally with research and development facilities in Boston and San Francisco, California, and a state-of-the-art manufacturing site in Framingham, Massachusetts. Its lead approved therapy, exagamglogene autotemcel (exa-cel, commercialized as CASGEVY in collaboration with Vertex Pharmaceuticals), is an autologous ex vivo CRISPR/Cas9 gene-edited cell therapy approved in multiple countries for eligible patients with sickle cell disease and transfusion-dependent beta-thalassemia; the company advances a broad pipeline including wholly owned and partnered programs across hemoglobinopathies such as next-generation conditioning agents and in vivo HSC editing; immuno-oncology and autoimmune therapies like CTX112 (anti-CD19 allogeneic CAR T) and other CAR T candidates targeting CD19, CD70, and glypican-3; in vivo cardiovascular programs including CTX310 (ANGPTL3), CTX320 (Lp(a)), and CTX340 (AGT for refractory hypertension); additional in vivo candidates such as CTX450 (ALAS1 for acute hepatic porphyria), CTX460 (SERPINA1 for alpha-1 antitrypsin deficiency), and undisclosed programs in rare and common diseases; regenerative medicine offerings like CTX211 and CTX213 (allogeneic gene-edited stem cell-derived therapies for type 1 diabetes); and partnered siRNA and other initiatives including SRSD107 (Factor XI for thromboembolic conditions with Sirius Therapeutics) and programs in Duchenne muscular dystrophy, myotonic dystrophy type 1, cystic fibrosis, and type 1 diabetes licensed to Vertex. In 2025, CRISPR Therapeutics expanded its portfolio through a strategic collaboration with Sirius Therapeutics, involving a $25 million cash upfront and $70 million equity investment to co-develop and commercialize novel siRNA therapies starting with SRSD107, with options for two additional programs and shared costs/profits; the company also continues global commercialization of CASGEVY, achieving regulatory approvals in nine countries and treating over 100 patients as of mid-2025 while advancing clinical milestones for CTX112, CTX310, CTX320, and others amid strong cash reserves exceeding $1.7 billion.

Company News

  • CRISPR Therapeutics AG (CRSP) Dips More Than Broader Market: What You Should Know

  • Here is What to Know Beyond Why CRISPR Therapeutics AG (CRSP) is a Trending Stock

  • Citi Sees 60% Upside in CRISPR Therapeutics. Here's What Has to Go Right.

  • CRISPR Therapeutics to Present Late-Breaking Data at the American Heart Association (AHA) Scientific Sessions 2026

  • CRISPR Therapeutics AG (CRSP) Stock Slides as Market Rises: Facts to Know Before You Trade

  • 3 Trending Names Overtaking Wall Street Today

  • Wall Street Bulls Look Optimistic About CRISPR Therapeutics (CRSP): Should You Buy?

  • CRISPR Therapeutics to Present Clinical Data on Zugocabtagene Geleucel (Zugo-cel) in Autoimmune Disease at the American College of Rheumatology (ACR) Convergence 2026

  • CRISPR Therapeutics AG (CRSP) is Attracting Investor Attention: Here is What You Should Know

  • CRISPR Therapeutics Has 2 Key Catalysts Coming by the End of 2026. Is the Market Underestimating Them?

  • CRISPR Therapeutics (NASDAQ:CRSP) & Septerna (NASDAQ:SEPN) Head-To-Head Survey

  • CRISPR Therapeutics (NASDAQ:CRSP) Stock: Insider James Kasinger Sells 10,400 Shares

  • CRISPR Therapeutics AG (CRSP) Stock Sinks As Market Gains: Here's Why

  • Crispr Therapeutics: Why AI Giant Anthropic's Discovery Has Rocked Gene Editing

  • CRISPR Therapeutics vs. Vertex Pharmaceuticals: Which Healthcare Stock Is a Better Buy in 2026?

  • CRISPR Therapeutics Traded Sideways and Down for 12 Months: One Wall Street Pro Expects 85% Gains Soon

  • 3 Reasons CRISPR Therapeutics Stock Is Still a Buy After a Rocky 2026

  • Where Will CRISPR Therapeutics Be in 10 Years if Gene Editing Fulfills Its Promise?

  • Wall Street Analysts Think CRISPR Therapeutics (CRSP) Is a Good Investment: Is It?

  • CRISPR Therapeutics AG (CRSP) Sees a More Significant Dip Than Broader Market: Some Facts to Know