CytomX Therapeutics, Inc.

CytomX Therapeutics, Inc.

CTMX
CytomX Therapeutics, Inc.US flagNASDAQ Global Select
3.01
USD
+0.03
- -
484.08MMarket Cap
2013 Y
2014 Y
2015 Y
2016 Y
2017 Y
2018 Y
2019 Y
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
0.03
0.15
0.9
0.42
1.93
1.43
0.59
1.48
0.58
0.81
1.37
1.64
0.55
0.23
Basic EPS, GAAP
-0.54
-1
-4.9
-1.63
-1.16
-2.03
-2.93
-1.4
-1.81
-1.51
-0.01
0.38
-0.13
-0.38
Free Cash Flow per Basic Share
-0.25
0.86
-3.38
-0.12
4.54
-1.9
-3.18
0.06
-1.88
-1.71
-0.77
-1.02
-0.55
-0.51
Dividend per Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Book Value per Share
-1.26
-2.24
-13.67
-4.87
-5.9
-7.56
-9.2
-11
-9.72
-11
-9.8
-8.19
-5.16
-4.65
Tangible Book Value per Share
-1.35
-2.33
14.35
2.09
1.81
3.08
1.08
-0.21
-0.04
-1.33
-0.67
-0.02
0.71
2.03
Basic Weighted Avg Shares
35
35
9
36
37
42
45
46
64
66
74
84
138
157
Sales/Revenue/Turnover
1
5
8
15
72
60
27
68
37
53
101
138
76
36
Operating Margin (%)
-1,684.23
-586.27
-430.54
-396.1
-64.59
-130.88
-525.92
-117.7
-311
-190.61
-6.41
18.1
-29.35
-181.92
Depreciation Expense
1
1
1
2
2
2
3
3
3
2
2
2
1
1
Net Income, GAAP
-15
-30
-35
-59
-43
-85
-133
-65
-116
-99
-1
32
-17
-59
Effective Tax Rate (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
117.12
0.7
- -
- -
Profit Margin (%)
-1,705.29
-597.01
-458.69
-391.54
-60.17
-142.19
-493.74
-94.73
-310.54
-186.82
-0.56
23.08
-22.79
-166.4
Working Capital
5
56
174
152
327
348
218
256
232
84
27
22
97
319
LT Debt
3
2
- -
- -
- -
- -
25
22
18
14
9
4
- -
- -
Total Equity
-44
-79
126
78
70
131
51
-8
- -
-86
-47
- -
99
320
Return on Invested Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
-202.25
- -
- -
Return on Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
0.08
-4.58
- -
- -
Return on Common Equity (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -

Capital Structure

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
ST Debt
6
4
3
LT Borrowings
- -
- -
- -
LT Finance Leases
- -
- -
- -
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
165
170
218
Market Capitalization
405
541
738

Working Capital

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
Total Current Assets
149
144
353
Cash, Cash Equivalents & STI
144
137
347
Accounts Receivable, Net
2
2
1
Inventories
- -
- -
- -
Total Current Liabilities
41
47
34
Payables & Accruals
13
15
13
ST Debt
6
4
3
Deferred Revenue
22
27
18

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
-360.55%
-693.59%
-21,812.28%
Free Cash Flow
-857.06%
-841.18%
-12.4%
Net Income, GAAP
-574.86%
-1,178.07%
-154.5%
Sales/Revenue/Turnover
63.28%
15.8%
-44.82%
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
41
25
33
38
138
2025
51
19
6
1
76
2026
10
- -
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
0.17
-0.08
0.07
- -
0.38
2025
0.27
- -
-0.09
- -
-0.13
2026
-0.1
- -
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Company Description

MCPAPIChat
CEO
Sean A. McCarthy
Full Time Employees
119
Sector
Healthcare
Industry
Biotechnology
Address
151 Oyster Point Boulevard South San Francisco CA United States of America 94080
IPO Date
Oct 8, 2015
Website
cytomx.com
Business
CytomX Therapeutics, Inc. is a clinical-stage oncology-focused biopharmaceutical company specializing in the development of novel conditionally activated biologics through its proprietary Probody® therapeutic platform. The company’s pipeline includes a range of therapeutics targeting cancer, such as antibody-drug conjugates (ADCs), T-cell engagers, and immune modulators including cytokines, designed to be activated specifically within the tumor microenvironment to enhance efficacy while minimizing systemic toxicity. CytomX’s main products and services encompass the development of masked biologics that address solid tumors by leveraging its Probody technology to improve tumor targeting and immune activation. The company operates primarily in the United States from its headquarters in South San Francisco, California, and collaborates with global biopharmaceutical partners including Astellas, Moderna, Amgen, Bristol Myers Squibb, and Regeneron. Founded in 2008, CytomX has recently advanced key clinical-stage programs such as CX-2051, a masked EpCAM-targeting ADC with a novel topoisomerase-1 payload focused on advanced colorectal cancer, and CX-801, a PROBODY interferon-alpha 2b cytokine undergoing trials in metastatic melanoma and other solid tumors. Significant 2024-2025 developments include initiating Phase 1 studies for these programs and entering strategic partnerships with Astellas for T-cell engager bispecific therapeutics and Moderna for mRNA-based conditionally activated therapies in oncology. The company also established a clinical collaboration with Merck to evaluate CX-801 in combination with the anti-PD-1 therapy Keytruda (pembrolizumab). Financially, CytomX reported $143.6 million in cash, cash equivalents, and investments as of Q3 2025, supporting ongoing clinical development and extending its cash runway into 2026 following a corporate restructuring. These operational and strategic advances reflect CytomX’s focus on developing next-generation immuno-oncology therapies that improve safety and effectiveness in cancer treatment.

Company News

MCPAPIChat
  • CytomX Therapeutics, Inc. (CTMX) Presents at Goldman Sachs 47th Annual Global Healthcare Conference 2026 Transcript

  • CytomX Announces Expansion of Strategic Research Collaboration with Regeneron in the Field of Conditional Bispecific Therapeutics for the Treatment of Cancer

  • CytomX Therapeutics: Cashed Up With Catalysts Ahead

  • CytomX Therapeutics to Present at Upcoming June Investor Conferences

  • CytomX Therapeutics Appoints Mamata Gokhale, Ph.D., RAC, as Senior Vice President of Regulatory Affairs

  • CytomX Therapeutics, Inc. (CTMX) Q1 2026 Earnings Call Transcript

  • CytomX Therapeutics (CTMX) Reports Q1 Loss, Beats Revenue Estimates

  • CytomX Therapeutics Announces Q1 2026 Financial Results and Provides Business Update

  • CytomX Therapeutics to Report First Quarter 2026 Financial Results on May 7, 2026

  • Small Cap or Megacap: Which Healthcare Stock Is Right for You?

  • Stock Traders Buy High Volume of CytomX Therapeutics Put Options (NASDAQ:CTMX)

  • CytomX Therapeutics (NASDAQ:CTMX) & Adagene (NASDAQ:ADAG) Financial Comparison

  • Assenagon Asset Management S.A. Sells 137,271 Shares of CytomX Therapeutics, Inc. $CTMX

  • CytomX Therapeutics (NASDAQ:CTMX) Shares Gap Up After Analyst Upgrade

  • Why Is CytomX Therapeutics Stock Falling On Wednesday?

  • CytomX Therapeutics: Great News, But Early Data Do Not Quite Justify This Price Level

  • CytomX Therapeutics Announces Pricing of $250 Million Offering of Common Stock and Pre-Funded Warrants

  • CTMX Stock Rallies on Strong Phase I Colorectal Cancer Study Data

  • Boothbay Fund Management LLC Buys Shares of 1,237,057 CytomX Therapeutics, Inc. $CTMX

  • Stock Market Today, March 16: CytomX Therapeutics Surges After Positive Phase 1 Colorectal Cancer Data