Pacific Biosciences of California, Inc.

Pacific Biosciences of California, Inc.

PACB
Pacific Biosciences of California, Inc.US flagNASDAQ Global Select
1.31
USD
-0.04
- -
406.89MMarket Cap
2013 Y
2014 Y
2015 Y
2016 Y
2017 Y
2018 Y
2019 Y
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
0.45
0.86
1.23
1.02
0.88
0.58
0.6
0.48
0.64
0.57
0.79
0.56
0.53
0.53
Basic EPS, GAAP
-1.26
-0.94
-0.42
-0.83
-0.87
-0.76
-0.55
0.18
-0.89
-1.4
-1.21
-1.13
-1.82
-0.43
Free Cash Flow per Basic Share
-0.49
-0.75
-0.67
-0.85
-0.74
-0.51
-0.53
0.11
-0.57
-1.25
-1.06
-0.77
-0.4
-0.4
Dividend per Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Book Value per Share
-9.8
-9.67
-9.43
-8.83
-8.32
-7.27
-6.99
-6.28
-5.97
-6.82
-7.25
-7.83
-8.98
-8.95
Tangible Book Value per Share
1.1
0.78
0.97
0.95
0.81
0.84
0.36
2.03
-0.15
-1.15
-0.86
-0.73
-1.09
-1.09
Basic Weighted Avg Shares
63
70
76
89
106
135
153
165
204
225
254
274
300
302
Sales/Revenue/Turnover
28
61
93
91
93
79
91
79
131
128
201
154
160
160
Operating Margin (%)
-275.16
-103.73
-56.24
-78.54
-96.06
-128.44
-110.62
-132.31
-136.51
-237.58
-154.78
-188.73
-348.46
-111.9
Depreciation Expense
6
4
4
4
8
7
10
9
12
17
27
53
386
18
Net Income, GAAP
-79
-66
-32
-74
-92
-103
-84
29
-181
-314
-307
-310
-546
-129
Effective Tax Rate (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Profit Margin (%)
-281.37
-109.19
-34.16
-81.99
-98.63
-130.44
-92.57
37.27
-138.85
-244.92
-152.97
-201.18
-341.47
-80.34
Working Capital
104
86
72
75
73
105
32
317
1,029
589
647
429
302
304
LT Debt
13
14
15
16
14
15
42
38
946
938
924
662
702
703
Total Equity
69
55
74
85
86
114
55
335
791
563
701
507
5
2
Return on Invested Capital (%)
- -
- -
- -
- -
- -
- -
- -
-42.25
- -
- -
- -
- -
- -
- -
Return on Capital (%)
- -
- -
- -
- -
- -
- -
- -
-2.97
- -
- -
- -
- -
- -
- -
Return on Common Equity (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -

Capital Structure

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
ST Debt
1
- -
- -
LT Borrowings
645
645
644
LT Finance Leases
54
57
59
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
302
302
310
Market Capitalization
378
561
399

Working Capital

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
Total Current Assets
394
375
370
Cash, Cash Equivalents & STI
299
280
276
Accounts Receivable, Net
31
35
29
Inventories
53
49
51
Total Current Liabilities
63
73
65
Payables & Accruals
46
54
48
ST Debt
1
- -
- -
Deferred Revenue
16
16
16

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
51.32%
0.96%
-98.94%
Free Cash Flow
-72.85%
-132.83%
-43.97%
Net Income, GAAP
-55.1%
-113.59%
76.34%
Sales/Revenue/Turnover
8.81%
20.15%
3.89%
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
39
36
40
39
154
2025
37
40
38
45
160
2026
37
- -
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
-0.26
-0.64
-0.22
0.01
-1.13
2025
-1.44
-0.14
-0.13
-0.13
-1.82
2026
-0.03
- -
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Company Description

MCPAPIChat
CEO
Christian O. Henry
Full Time Employees
575
Sector
Healthcare
Industry
Medical - Devices
Address
1305 O’Brien Drive Menlo Park CA United States of America 94025
IPO Date
Oct 27, 2010
Website
pacb.com
Business
Pacific Biosciences of California, Inc. (PacBio) designs, develops, and manufactures advanced sequencing solutions to resolve genetically complex problems in life sciences research and clinical applications; its core offerings include long-read HiFi sequencing systems such as the Revio production-scale platform delivering up to 120 Gb per SMRT Cell with SPRQ-Nx chemistry, the Vega benchtop system providing 60 Gb per SMRT Cell, and legacy Sequel II and Sequel IIe instruments; short-read sequencing via the Onso system powered by sequencing by binding (SBB) chemistry achieving 90% Q40 accuracy; consumables encompassing SMRTbell library preparation kits, reagent kits including ligase, buffers, exonucleases, flow cells, clustering, and sequencing reagents; and software solutions like SMRT Link for analysis, Paraphase variant caller, and applications for whole genome sequencing, targeted sequencing, epigenetics, RNA isoform sequencing, and PureTarget assays for repeat expansions and carrier screening. The company serves academic and governmental research institutions, genome centers, public health labs, hospitals, clinical research institutes, contract research organizations, pharmaceutical firms, and agricultural companies across the Americas, Europe, Middle East, Africa, Asia Pacific including China and Japan, and other regions through direct sales and distribution partners. Incorporated in 2000 and headquartered at 1305 O'Brien Drive in Menlo Park, California, PacBio operates in the biotechnology sector focusing on human genetics, plant and animal sciences, infectious disease, oncology, and emerging multiomic applications. Recent developments include the launch of SPRQ-Nx chemistry in 2025 targeting up to 40% reduction in HiFi genome sequencing costs to under $300 per genome at scale with beta testing on Revio starting November 2025 and commercial availability in 2026; expanded PureTarget portfolio with updated repeat expansion and new carrier screening panels plus 96-plex automation kits; distribution agreement with Haorui Gene in 2025 to promote platforms including Vega in China's clinical labs for blood typing genomics and precision medicine; Class III medical device approval in China for Sequel II CNDx system via partner Berry Genomics in November 2025; partnership with Epicycle for FiberSeq chromatin analysis integration; selection of Revio for the U.S. National Institute on Aging's Long Life Family Study sequencing up to 7,800 genomes and epigenomes, and the Korean Pangenome Reference Project for over 1,000 genomes; and publication of HiFi Solves EMEA Consortium preprint demonstrating 100% detection of pathogenic variants in complex regions.

Company News

MCPAPIChat
  • Pacific Biosciences of California (PACB) Stock Sinks As Market Gains: Here's Why

  • Here's Why You Should Add PacBio Stock to Your Portfolio Now

  • 3 Promising Genomics & Synthetic Biology Stocks in Spotlight in 2026

  • PacBio Expands HiFi Sequencing Reach With New SPRQ-Nx Technology

  • PacBio SPRQ-Nx Chemistry Now Shipping Worldwide, Enabling Sub-$300 HiFi Genomes for Large Scale Projects and AI-Enhanced Sequencing

  • PacBio to Participate in the Jefferies Global Healthcare Conference

  • PACB & Blank Bio Partner to Advance RNA Foundation Models in Oncology

  • Blank Bio Announces Seed Financing and Strategic Collaboration with PacBio to Advance RNA Foundation Models for Precision Oncology

  • HiFi Solves Sub-fertility Consortium in Asia Pacific Reports First Major Study Using HiFi Long-Read Sequencing to Investigate Unexplained Subfertility and Recurrent Pregnancy Loss

  • Pacific Biosciences of California Q1 Earnings Call Highlights

  • PACB Q1 Earnings Beat, Revenues Miss Estimates, Gross Margin Down

  • Pacific Biosciences of California, Inc. (PACB) Q1 2026 Earnings Call Transcript

  • Pacific Biosciences of California (PACB) Reports Q1 Loss, Lags Revenue Estimates

  • PacBio Announces First Quarter 2026 Financial Results

  • PacBio Pre-Q1 Analysis: Time to Buy, Hold or Sell the Stock Now?

  • Critical Review: Autonomix Medical (NASDAQ:AMIX) and Pacific Biosciences of California (NASDAQ:PACB)

  • Pacific Biosciences of California (PACB) Stock Declines While Market Improves: Some Information for Investors

  • PacBio & Lucid Genomics Partner to Boost Data Analysis, Stock Up

  • PacBio and Lucid Genomics Announce Compatibility Collaboration to Advance Tertiary Analysis for Long-Read Sequencing

  • PacBio Stock Up on New FFPE Workflow Boosting Cancer Sequencing