Denali Therapeutics Inc.

Denali Therapeutics Inc.

DNLI
Denali Therapeutics Inc.US flagNASDAQ Global Select
24.77
USD
+0.72
- -
3.93BMarket Cap
2015 Y
2016 Y
2017 Y
2018 Y
2019 Y
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
- -
- -
- -
1.39
0.28
3.08
0.4
0.86
2.41
- -
- -
- -
Basic EPS, GAAP
-5.58
-13.49
-5.89
-0.39
-2.07
0.65
-2.39
-2.6
-1.06
-2.57
-2.97
-2.88
Free Cash Flow per Basic Share
-6.03
-12.15
-5.31
0.5
-1.77
3.79
-1.81
-2.09
-2.7
-2.21
-2.44
-2.38
Dividend per Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Book Value per Share
-5.55
-16.06
-12.73
-2.45
-4.44
-3.24
-5.29
-7.72
-8.11
-9.35
-11.87
-12.34
Tangible Book Value per Share
-5.2
-14.65
31.13
5.9
4.13
10.56
7.92
8.3
7.5
7.48
5.87
5.04
Basic Weighted Avg Shares
3
6
15
93
96
109
122
126
137
164
173
176
Sales/Revenue/Turnover
- -
- -
- -
129
27
336
49
108
331
- -
- -
- -
Operating Margin (%)
- -
- -
- -
-35.9
-799.1
18.69
-607.78
-314.16
-59.51
- -
- -
- -
Depreciation Expense
- -
1
3
7
8
9
9
10
17
9
15
15
Net Income, GAAP
-17
-87
-88
-36
-198
71
-291
-326
-145
-423
-513
-508
Effective Tax Rate (%)
- -
- -
- -
- -
- -
1.14
- -
- -
- -
- -
- -
- -
Profit Margin (%)
- -
- -
- -
-28.06
-740.74
21.19
-597.15
-300.56
-43.94
- -
- -
- -
Working Capital
30
173
395
448
385
1,424
519
1,008
986
762
802
913
LT Debt
- -
- -
- -
- -
69
64
59
53
45
37
27
25
Total Equity
-16
-94
466
547
395
1,151
962
1,042
1,031
1,230
1,014
926
Return on Invested Capital (%)
- -
- -
- -
- -
- -
7.35
- -
- -
- -
- -
- -
- -
Return on Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Common Equity (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -

Capital Structure

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
ST Debt
9
10
10
LT Borrowings
- -
- -
- -
LT Finance Leases
35
27
25
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
147
156
159
Market Capitalization
2,487
2,850
3,389

Working Capital

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
Total Current Assets
883
901
1,023
Cash, Cash Equivalents & STI
848
868
988
Accounts Receivable, Net
- -
2
- -
Inventories
- -
- -
- -
Total Current Liabilities
90
98
110
Payables & Accruals
40
36
76
ST Debt
9
10
10
Deferred Revenue
- -
- -
- -

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
8.11%
-1.48%
-17.56%
Free Cash Flow
-71.09%
-15.69%
16.09%
Net Income, GAAP
32.89%
-67.88%
21.23%
Sales/Revenue/Turnover
- -
- -
- -
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
-0.68
-0.59
-0.63
-0.67
-2.57
2025
-0.78
-0.72
-0.74
-0.73
-2.97
2026
-0.69
- -
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Company Description

APIChatGPT
CEO
Ryan J. Watts
Full Time Employees
443
Sector
Healthcare
Industry
Biotechnology
Address
161 Oyster Point Boulevard South San Francisco CA United States of America 94080
IPO Date
Dec 8, 2017
Business
Denali Therapeutics Inc. (NASDAQ: DNLI) develops therapies for neurodegenerative and lysosomal storage diseases. The company focuses on programs targeting Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis (ALS), and mucopolysaccharidosis type IIIA (MPS IIIA), including DNL343 for ALS and frontotemporal dementia, DNL788 for ALS and Parkinson's, tividenofusp alfa for MPS IIIA, and buntanetap for Alzheimer's; it also advances discovery efforts in other rare diseases. Founded in 2015 and headquartered in South San Francisco, California, Denali operates primarily in the United States with a pipeline built on its proprietary Engineered Antibody Transport (ATLAS) and Enzyme Transport Vehicle (ETV) technologies for crossing the blood-brain barrier. Denali Therapeutics serves the biopharmaceutical industry, targeting patients with neurodegenerative disorders through clinical-stage assets and research collaborations. Its geographic operations center in the U.S., with global partnerships extending research impact. The company maintains subsidiaries like Denali Medtech Inc. for manufacturing support.

Company News

APIChatGPT
  • Denali to Sell Priority Review Voucher for $195M Cash Boost

  • Denali Therapeutics Enters Agreement to Sell Rare Pediatric Disease Priority Review Voucher for $195 Million

  • Denali Therapeutics Inc. (DNLI) Presents at Jefferies Global Healthcare Conference 2026 Transcript

  • Denali Therapeutics: 'Strong Buy' On AVLAYAH Approval And End Of 2026 FTD-GRN Data

  • Denali Stock Dips as Biogen-Partnered Parkinson's Disease Study Fails

  • Hedge Fund Wagers $36 Million on Biotech Denali After First FDA Approval

  • Denali Therapeutics Says AVLAYAH Launch Ahead of Expectations After Hunter Syndrome Approval

  • Denali Therapeutics Inc. (DNLI) Presents at Bank of America Global Healthcare Conference 2026 Transcript

  • DNLI Q1 Loss Narrower Than Expected, Avlayah Approval Boosts Prospects

  • Denali Therapeutics Reports First Quarter 2026 Financial Results and Business Highlights

  • Privium Fund Opens $5.07 Million Denali Stake Ahead of FDA Drug Approval

  • Denali: The First Commercial Validation Of The Blood-Brain Barrier Platform

  • DNLI Gains 25.4% Year to Date: Should You Buy, Sell or Hold the Stock?

  • Denali Stock Falls as Partner Takeda Ends Collaboration Deal

  • Takeda Exits Dementia Drug Partnership With Denali Therapeutics - Here's Why

  • Capricorn Fund Managers Ltd Acquires New Position in Denali Therapeutics Inc. $DNLI

  • SG Americas Securities LLC Increases Stock Position in Denali Therapeutics Inc. $DNLI

  • Denali Therapeutics Inc. (NASDAQ:DNLI) Receives Average Rating of “Moderate Buy” from Analysts

  • Denali Therapeutics Regains Full Rights to Investigational Therapy DNL593 (PTV:PGRN) for GRN-related Frontotemporal Dementia (FTD-GRN)

  • Denali Wins FDA Nod for Hunter Syndrome Drug, Stock Up